Acquired universal melanosis (Carbon baby syndrome) in a 4-year old girl

Mediterranean Stomatocytosis/macrothrombocytopenia in A 9-Year-Old Girl

Multifocal tumoral calcinosis in a 4-year-old girl

PATIENT Female, 4 FINAL DIAGNOSIS: Tumoral calcinosis Symptoms: Hard immobile mass Medication: - Clinical Procedure: - Specialty: Surgery. OBJECTIVE Congenital defects. BACKGROUND Tumoral calcinosis is an uncommon condition associated with the deposition of painless calcific masses. It is more common in childhood or early adolescence of African-American females. CASE REPORT We present a c...

Congenital generalized lipodystrophy in a 4 year old Chinese girl.

Congenital generalized lipodystrophy (CGL) is a rare autosomal recessive disorder characterized by near complete absence of adipose tissue since birth and insulin resistance. The diagnosis is made on the basis of lack of body fat, muscular hypertrophy, acanthosis nigricans, hirsutism, hepatomegaly with fatty liver, hyperlipidemia and hyperglycemia with insulin resistance. We describe a 4-year-o...

Unilateral sight loss in a 4-year-old girl.

For 6 weeks the parents of a 4-year-old girl had noticed a difference between the two eyes of their child. Ophtalmological examination revealed leukocoria. This finding raised clinical suspicion of retinoblastoma. MRI was performed. On T2 weighted images a hypointense mass relative to the vitreous humor was evident. There were several hypointensities compatible with calcifications. An area of r...

Juvenile dermatomyositis in a 4‐year‐old Kenyan girl

To our knowledge, this is the first case report of juvenile dermatomyositis (JDM) in Tanzania. It demonstrates that the characteristic cutaneous findings of JDM may easily be overlooked, especially on dark skin, and the difficulty of clinical management in resource-constrained settings.

Macroamylasemia in a 4-year-old girl with abdominal pain

Macroamylasemia is a benign condition characterized by abnormally large-sized serum amylase; it has been reported to occur in 1–2% of the population. In macroamylasemia, a macromolecular complex consisting of amylase linked to immunoglobulins circulates in the plasma and usually causes hyperamylasemia with low or normal amylasuria. Macroamylasemia is extremely rare in children. We report a case...